Search results for " Radio-Iodinated"

showing 3 items of 3 documents

Extracellular space and electrolyte distribution in cortex and white matter of dog brain in cold induced oedema

1973

24 hours after a circumscribed cold injury of the cortex dog brains were perfused from the lateral ventricle and the frontal subarachnoidal space to the cisterna magna with an artificial CSF containing trace amounts of35S-labelled thiosulphate. Simultaneously the extracellular tracer was administered intravenously. Extracellular fluid volume was estimated and found to be increased from 10 to 15% in the oedematous cortex and from 10 to 27% in the oedematous white matter. The actual size of ECS in oedematous white matter, however, must be larger as indicated by the relative alterations of thiosulphate distribution, tissue water, sodium and chloride. Apparently a small part of the fluid accumu…

Pathologymedicine.medical_specialtySodiumThiosulfateschemistry.chemical_elementBrain EdemaCisterna magnaIodine RadioisotopesWhite matterchemistry.chemical_compoundDogsChloridesCortex (anatomy)Sulfur IsotopesExtracellular fluidExtracellularAnimalsMedicineSerum Albumin Radio-IodinatedEvans BlueCerebral CortexStaining and Labelingbusiness.industrySodiumWater-Electrolyte BalanceCold TemperatureDisease Models Animalmedicine.anatomical_structurechemistryBlood-Brain BarrierCerebral cortexPotassiumSurgeryNeurology (clinical)Extracellular SpacebusinessActa Neurochirurgica
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Autoradiographic technique to assess distribution of blood flow within organs

1969

A method is described for assessing the distribution of blood flow within organs. Microspheres, 5–50 μ in diameter, labelled with a beta-emitting isotope were injected into the left ventricle of experimental animals. The distribution of the indicator within the tissues, which is assumed to represent the regional distribution of flow, was visualized and measured quantitatively by autoradiography. Local flow rates in areas of about 1,2 mm in diameter could be determined. Application of the technique for the study of regional myocardial and renal circulation is demonstrated.

PhysiologyClinical BiochemistryKidneyRadioactive microspheresMicrosphereDogsPhysiology (medical)MethodsmedicineAnimalsDistribution (pharmacology)Serum Albumin Radio-IodinatedRenal circulationIsotopeChemistryBrainBlood flowHuman physiologyAnatomyCoronary Vesselsmedicine.anatomical_structureRegional Blood FlowVentricleCatsAutoradiographyRabbitsPfl�gers Archiv European Journal of Physiology
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Regional distribution of blood flow in the renal cortex

1969

Es wird ein autoradiographisches Verfahren zur Bestimmung der regionalen Durchblutungsverteilung in differenziert strukturierten Organen beschrieben. Mit dieser neuen Methode wird die Durchblutung der Nierenrinde untersucht. Es wird nachgewiesen, dass die Durchblutungs- bzw. Widerstandsverteilung innerhalb der Rinde nicht einheitlich ist, sondern dass sich drei verschieden durchblutete, anatomisch voneinander abgrenzbare Teile unterscheiden lassen.

PharmacologyChemistryRenal cortexCell BiologyBlood flowKidneyMolecular biologyCellular and Molecular NeuroscienceDogsmedicine.anatomical_structureRegional Blood FlowMethodsmedicineAnimalsAutoradiographyMolecular MedicineSerum Albumin Radio-IodinatedMolecular BiologyExperientia
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